Proposed Biosecurity Oversight Framework for the Future of Science

Proposed Biosecurity Oversight Framework for the Future of Science

US government charged NSABB with "evaluating and providing recommendations on the effectiveness of two major US biosecurity policy frameworks governing" research with enhanced potential pandemic pathogens (ePPP) and dual use research of concern.

2022

“The current scope of the DURC policies is limited, and the list-based approach to oversight is inherently less adaptive than other potential approaches”. In place of a list-based approach, P3CO approach requires oversight of all research that is “reasonably anticipated to create, transfer, or use a PPP resulting from the enhancement of the transmissibility of virulence in humans of any pathogen”. Research involving 1+ agents that produces, aims to produce, or can be anticipated to produce 7+ categories of experimental effects (translated into criteria) must be evaluated for potential DURC.